Melanocytes and Pigmentation Are Affected in Dopachrome Tautomerase Knockout Mice

The tyrosinase family comprises three members, tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1), and dopachrome tautomerase (Dct). Null mutations and deletions at the Tyr and Tyrp1 loci are known and phenotypically affect coat color due to the absence of enzyme or intracellular mislocalization...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Guyonneau, Laurence, Murisier, Fabien, Rossier, Anita, Moulin, Alexandre, Beermann, Friedrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2004
Gaiak:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.8.3396-3403.2004
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