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Melanocytes and Pigmentation Are Affected in Dopachrome Tautomerase Knockout Mice
The tyrosinase family comprises three members, tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1), and dopachrome tautomerase (Dct). Null mutations and deletions at the Tyr and Tyrp1 loci are known and phenotypically affect coat color due to the absence of enzyme or intracellular mislocalization...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC381679/ https://ncbi.nlm.nih.gov/pubmed/15060160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.8.3396-3403.2004 |
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