Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

Disruption of lymphatic lipid transport is linked to obesity and type 2 diabetes (T2D), but regulation of lymphatic vessel function and its link to disease remain unclear. Here we show that intestinal lymphatic endothelial cells (LECs) have an increasing CD36 expression from lymphatic capillaries (l...

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Vydáno v:Nat Commun
Hlavní autoři: Cifarelli, Vincenza, Appak-Baskoy, Sila, Peche, Vivek S., Kluzak, Andrew, Shew, Trevor, Narendran, Ramkumar, Pietka, Kathryn M., Cella, Marina, Walls, Curtis W., Czepielewski, Rafael, Ivanov, Stoyan, Randolph, Gwendalyn J., Augustin, Hellmut G., Abumrad, Nada A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184948/
https://ncbi.nlm.nih.gov/pubmed/34099721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23808-3
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