Visceral obesity and insulin resistance associate with CD36 deletion in lymphatic endothelial cells

Disruption of lymphatic lipid transport is linked to obesity and type 2 diabetes (T2D), but regulation of lymphatic vessel function and its link to disease remain unclear. Here we show that intestinal lymphatic endothelial cells (LECs) have an increasing CD36 expression from lymphatic capillaries (l...

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Publicat a:Nat Commun
Autors principals: Cifarelli, Vincenza, Appak-Baskoy, Sila, Peche, Vivek S., Kluzak, Andrew, Shew, Trevor, Narendran, Ramkumar, Pietka, Kathryn M., Cella, Marina, Walls, Curtis W., Czepielewski, Rafael, Ivanov, Stoyan, Randolph, Gwendalyn J., Augustin, Hellmut G., Abumrad, Nada A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184948/
https://ncbi.nlm.nih.gov/pubmed/34099721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23808-3
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