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A small molecule HIF-1α stabilizer that accelerates diabetic wound healing
Impaired wound healing and ulcer complications are a leading cause of death in diabetic patients. In this study, we report the design and synthesis of a cyclometalated iridium(III) metal complex 1a as a stabilizer of hypoxia-inducible factor-1α (HIF-1α). In vitro biophysical and cellular analyses de...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184911/ https://ncbi.nlm.nih.gov/pubmed/34099651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23448-7 |
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