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Amphotericin B induces epithelial voltage responses in people with cystic fibrosis

BACKGROUND: Approximately 10% of people with cystic fibrosis (CF) have mutations that result in little to no CFTR production and thus cannot benefit from CFTR modulators. We previously found that Amphotericin B (AmB), a small molecule that forms anion channels, restored HCO(3)(−) secretion and incre...

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Detaylı Bibliyografya
Yayımlandı:J Cyst Fibros
Asıl Yazarlar: Chorghade, Rajeev S., Kim, Bo Ram, Launspach, Janice L., Karp, Philip H., Welsh, Michael J., Burke, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184863/
https://ncbi.nlm.nih.gov/pubmed/33309058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2020.11.018
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