5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis

BACKGROUND: Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps. Polyp resection prevents progression to CRC. Risk of future polyps is proportional to the number and size of polyps detected at screening, allowing identification of high-risk individuals who may ben...

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Vydáno v:Br J Cancer
Hlavní autoři: Dixon, Steven William, Collard, Tracey Jane, Mortensson, Eleanor May Harrisdotter, Legge, Danny Nigel, Chambers, Adam Christian, Greenhough, Alexander, Creed, Tom Julian, Williams, Ann Caroline
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184823/
https://ncbi.nlm.nih.gov/pubmed/33785874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01354-5
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