An Inhaled PI3Kδ Inhibitor Improves Recovery in Acutely Exacerbating COPD Patients: A Randomized Trial

PURPOSE: This study evaluated the safety and efficacy of inhaled nemiralisib, a phosphoinositide 3-kinase δ (PI3Kδ) inhibitor, in patients with an acute exacerbation of chronic obstructive pulmonary disease (COPD). METHODS: In this double-blind, placebo-controlled study, 126 patients (40–80 years wi...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Cahn, Anthony, Hamblin, J Nicole, Robertson, Jon, Begg, Malcolm, Jarvis, Emily, Wilson, Robert, Dear, Gordon, Leemereise, Claudia, Cui, Yi, Mizuma, Maki, Montembault, Mickael, Van Holsbeke, Cedric, Vos, Wim, De Backer, Wilfried, De Backer, Jan, Hessel, Edith M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184151/
https://ncbi.nlm.nih.gov/pubmed/34113093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S309129
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