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Targeting EML4-ALK gene fusion variant 3 in thyroid cancer

Finding targetable gene fusions can expand the limited treatment options in radioactive iodine-refractory (RAI-r) thyroid cancer. To that end, we established a novel cell line ‘JVE404’ derived from an advanced RAI-r papillary thyroid cancer (PTC) patient, harboring an EML4-ALK gene fusion variant 3...

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Dettagli Bibliografici
Pubblicato in:Endocr Relat Cancer
Autori principali: Aydemirli, Mehtap Derya, van Eendenburg, Jaap D H, van Wezel, Tom, Oosting, Jan, Corver, Willem E, Kapiteijn, Ellen, Morreau, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bioscientifica Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183637/
https://ncbi.nlm.nih.gov/pubmed/33878728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-20-0436
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