Orphan nuclear receptor COUP‐TFII enhances myofibroblast glycolysis leading to kidney fibrosis

Recent studies demonstrate that metabolic disturbance, such as augmented glycolysis, contributes to fibrosis. The molecular regulation of this metabolic perturbation in fibrosis, however, has been elusive. COUP‐TFII (also known as NR2F2) is an important regulator of glucose and lipid metabolism. Its...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Li, Li, Galichon, Pierre, Xiao, Xiaoyan, Figueroa‐Ramirez, Ana C, Tamayo, Diana, Lee, Jake J‐K, Kalocsay, Marian, Gonzalez‐Sanchez, David, Chancay, Maria S, McCracken, Kyle W, Lee, Nathan N, Ichimura, Takaharu, Mori, Yutaro, Valerius, M Todd, Wilflingseder, Julia, Lemos, Dario R, Edelman, Elazer R, Bonventre, Joseph V
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183413/
https://ncbi.nlm.nih.gov/pubmed/34031962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051169
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