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Anti-Seizure Activity of 1-Adamantane Carboxylic Acid in Common Experimental Seizure Models: Role of Benzodiazepine-GABA(A) Receptors

BACKGROUND: Despite introduction of modern antiepileptic drugs, 30% of epileptic patients are still drug resistant. Remarkable three-dimensional spatial structure of AdCA, yet the simplicity of the molecule, makes AdCA a promising lead compound. METHODS: Sedative/motor impairment and 24-h mortality...

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Bibliografiske detaljer
Udgivet i:Iran Biomed J
Main Authors: Ghanbari, Elham, Gavzan, Hakimeh, Khoshkroodian, Bahar, Sayyah, Mohammad
Format: Artigo
Sprog:Inglês
Udgivet: Pasteur Institute of Iran 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183385/
https://ncbi.nlm.nih.gov/pubmed/33653022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.52547/ibj.25.3.213
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