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Possible alterations in GABA(A) receptor signaling that underlie benzodiazepine-resistant seizures

Benzodiazepines have been used for decades as the first-line treatment for status epilepticus (SE). For reasons that are not fully understood, the efficacy of benzodiazepines decreases with increasing durations of seizure activity. This often forces clinicians to resort to more drastic second- and t...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Deeb, Tarek Z., Maguire, Jamie, Moss, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402207/
https://ncbi.nlm.nih.gov/pubmed/23216581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12037
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