Design, synthesis and immunological evaluation of self-assembled antigenic peptides from dual-antigen targets: a broad-spectrum candidate for an effective antibreast cancer therapy

BACKGROUND: Considering the narrow immune response spectrum of a single epitope, and the nanoparticles (NPs) as a novel adjuvant can achieve efficient delivery of antigenic peptides safely, a nano-system (denoted as DSPE-PEG-Man@EM-NPs) based on cathepsin B-responsive antigenic peptides was designed...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Shi, Wei, Qiu, Qianqian, Feng, Ziying, Tong, Zhenzhen, Guo, Weiwei, Zou, Feng, Yue, Na, Huang, Wenlong, Qian, Hai
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Basic Tumor Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183215/
https://ncbi.nlm.nih.gov/pubmed/34083420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002523
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