Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency

Patients with mutations of the recombination-activating genes (RAG) present with diverse clinical phenotypes, including severe combined immune deficiency (SCID), autoimmunity, and inflammation. However, the incidence and extent of immune dysregulation in RAG-dependent immunodeficiency have not been...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Walter, Jolan E., Rosen, Lindsey B., Csomos, Krisztian, Rosenberg, Jacob M., Mathew, Divij, Keszei, Marton, Ujhazi, Boglarka, Chen, Karin, Lee, Yu Nee, Tirosh, Irit, Dobbs, Kerry, Al-Herz, Waleed, Cowan, Morton J., Puck, Jennifer, Bleesing, Jack J., Grimley, Michael S., Malech, Harry, De Ravin, Suk See, Gennery, Andrew R., Abraham, Roshini S., Joshi, Avni Y., Boyce, Thomas G., Butte, Manish J., Nadeau, Kari C., Balboni, Imelda, Sullivan, Kathleen E., Akhter, Javeed, Adeli, Mehdi, El-Feky, Reem A., El-Ghoneimy, Dalia H., Dbaibo, Ghassan, Wakim, Rima, Azzari, Chiara, Palma, Paolo, Cancrini, Caterina, Capuder, Kelly, Condino-Neto, Antonio, Costa-Carvalho, Beatriz T., Oliveira, Joao Bosco, Roifman, Chaim, Buchbinder, David, Kumanovics, Attila, Franco, Jose Luis, Niehues, Tim, Schuetz, Catharina, Kuijpers, Taco, Yee, Christina, Chou, Janet, Masaad, Michel J., Geha, Raif, Uzel, Gulbu, Gelman, Rebecca, Holland, Steven M., Recher, Mike, Utz, Paul J., Browne, Sarah K., Notarangelo, Luigi D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639965/
https://ncbi.nlm.nih.gov/pubmed/26457731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80477
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