CHOP Regulates Endoplasmic Reticulum Stress-Mediated Hepatoxicity Induced by Monocrotaline

Monocrotaline (MCT), a pyrrolizidine alkaloid, is the major toxin in Crotalaria, which causes cell apoptosis in humans and animals. It has been reported that the liver is a vulnerable target of MCT. However, the exact molecular mechanism of the interaction between endoplasmic reticulum (ER) stress a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Guo, Yazhou, Yang, Chen, Guo, Rong, Huang, Ruijie, Su, Yongxia, Wang, Shuai, Kong, Yezi, Wang, Jianguo, Tan, Chengjian, Mo, Chonghui, Wu, Chenchen, Zhao, Baoyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181757/
https://ncbi.nlm.nih.gov/pubmed/34108882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.685895
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