Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress

The regulatory control of cardiac endoplasmic reticulum (ER) stress is incompletely characterized. As ER stress signaling upregulates the E3-ubiquitin ligase Parkin, we investigated the role of Parkin in cardiac ER stress. Parkin knockout mice exposed to aortic constriction-induced cardiac pressure-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Han, Kim, Hassanzadeh, Shahin, Singh, Komudi, Menazza, Sara, Nguyen, Tiffany T., Stevens, Mark V., Nguyen, An, San, Hong, Anderson, Stasia A., Lin, Yongshun, Zou, Jizhong, Murphy, Elizabeth, Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437023/
https://ncbi.nlm.nih.gov/pubmed/28522833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02339-2
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