CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis

Free fatty acid induction of inflammation and cell death is an important feature of nonalcoholic steatohepatitis (NASH) and has been associated with disruption of the endoplasmic reticulum and activation of the unfolded protein response (UPR). After chronic UPR activation, the transcription factor C...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Willy, Jeffrey A., Young, Sara K., Stevens, James L., Masuoka, Howard C., Wek, Ronald C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2015
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462938/
https://ncbi.nlm.nih.gov/pubmed/25904325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-01-0036
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