Formulation of sublingual promethazine hydrochloride tablets for rapid relief of motion sickness

The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop a sublingual formulation of promethazine hydrochloride by direct compression, and to mask its intensely bitter taste. Promethazine hydrochloride (PMZ) sublingual tabl...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Alyami, Hamad S, Ibrahim, Mohamed A., Alyami, Mohammad H., Dahmash, Eman Z, Almeanazel, Osaid T., Algahtani, Thamer S, Alanazi, Fars, Alshora, Doaa H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180616/
https://ncbi.nlm.nih.gov/pubmed/34135674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2021.04.011
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