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Rosuvastatin calcium nanoparticles: Improving bioavailability by formulation and stabilization codesign
PURPOSE: Rosuvastatin calcium (ROSCa) is a poorly soluble drug with bioavailability not exceeding 20%. Decreasing the particle size may enhance its solubility, dissolution rate and bioavailability. Therefore, the aim of the current study is to prepare ROSCa nanoparticles by wet milling technique usi...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037357/ https://ncbi.nlm.nih.gov/pubmed/29985967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200218 |
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