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Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073

The design and synthesis of narrow-spectrum antibiotics that target a specific bacterial strain, species, or group of species is a promising strategy for treating bacterial infections when the causative agent is known. In this work, we report the synthesis and evaluation of four new siderophore-β-la...

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Vydáno v:Chem Sci
Hlavní autoři: Sargun, Artur, Johnstone, Timothy C., Zhi, Hui, Raffatellu, Manuela, Nolan, Elizabeth M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society of Chemistry 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179508/
https://ncbi.nlm.nih.gov/pubmed/34163675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04337k
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