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Palladium catalyzed synthesis of indolizines via the carbonylative coupling of bromopyridines, imines and alkynes
We report herein the development of a palladium-catalyzed, multicomponent synthesis of indolizines. The reaction proceeds via the carbonylative formation of a high energy, mesoionic pyridine-based 1,3-dipole, which can undergo spontaneous cycloaddition with alkynes. Overall, this provides a route to...
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| Publicado en: | Chem Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Royal Society of Chemistry
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8179343/ https://ncbi.nlm.nih.gov/pubmed/34163991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03977b |
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