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A DNA-mediated crosslinking strategy to enhance cellular delivery and sensor performance of protein spherical nucleic acids

Intracellular delivery of enzymes is essential for protein-based diagnostic and therapeutic applications. Protein-spherical nucleic acids (ProSNAs) defined by protein core and dense shell of oligonucleotides have been demonstrated as a promising vehicle-free enzyme delivery platform. In this work, w...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Yan, Jing, Tan, Ya-Ling, Lin, Min-jie, Xing, Hang, Jiang, Jian-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179099/
https://ncbi.nlm.nih.gov/pubmed/34163943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04977h
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