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Interaction of 8-anilinonaphthalene-1-sulfonate with SARS-CoV-2 main protease and its application as a fluorescent probe for inhibitor identification
The 3C-like main protease of SARS-CoV-2 (3CL(Pro)) is responsible for the cleavage of the viral polyprotein. This process is essential for the viral life cycle. Therefore, 3CL(Pro) is a promising target to develop antiviral drugs for COVID-19 prevention and treatment. Traditional enzymatic assays fo...
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| Опубликовано в: : | Comput Struct Biotechnol J |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Research Network of Computational and Structural Biotechnology
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178945/ https://ncbi.nlm.nih.gov/pubmed/34109016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.053 |
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