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Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation

BACKGROUND: Neuroinflammation has been identified to be the key player in most neurodegenerative diseases. If neuroinflammation is left to be unresolved, chronic neuroinflammation will be establish. Such situation is due to the overly-activated microglia which have the tendency to secrete an abundan...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Biotechnol
Hauptverfasser: Yahaya, M. A. F., Bakar, A. R. Abu, Stanslas, J., Nordin, N., Zainol, M., Mehat, M. Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178909/
https://ncbi.nlm.nih.gov/pubmed/34090414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-021-00697-4
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