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Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Attenuates High-Fat Diet-Induced Hepatic Steatosis in Mice
INTRODUCTION: The effect of 11β-hydroxysteroid dehydrogenase type1 (11β-HSD1) inhibition on hepatic steatosis is incompletely understood. Here, we aimed to determine the therapeutic effect of BVT.2733, a selective 11β-HSD1 inhibitor, on hepatic steatosis. MATERIALS AND METHODS: C57B/6J mice were ran...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178584/ https://ncbi.nlm.nih.gov/pubmed/34103895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S285828 |
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