BVT.2733, a Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Attenuates Obesity and Inflammation in Diet-Induced Obese Mice

BACKGROUND: Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic syndrome. Therefore, there is an urgent need to determine the effect of 11β-HSD1 inhibitor, which suppresses glucocorticoid action, o...

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Detalhes bibliográficos
Main Authors: Wang, Long, Liu, Juan, Zhang, Aisen, Cheng, Peng, Zhang, Xiao, Lv, Shan, Wu, Lin, Yu, Jing, Di, Wenjuan, Zha, Juanmin, Kong, Xiaocen, Qi, Hanmei, Zhong, Yi, Ding, Guoxian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388048/
https://ncbi.nlm.nih.gov/pubmed/22768329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040056
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