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Smac-mimetic enhances antitumor effect of standard chemotherapy in ovarian cancer models via Caspase 8-independent mechanism

Ovarian cancer is the most lethal gynecological cancer in the US. Standard treatment consists of surgery followed by chemotherapies relying on apoptotic tumor cell death. Most women with advanced stage disease will relapse, suggesting that this disease is characterized by primary and acquired resist...

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Foilsithe in:Cell Death Discov
Main Authors: Hernandez, Lidia F., Dull, Angie B., Korrapati, Soumya, Annunziata, Christina M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178341/
https://ncbi.nlm.nih.gov/pubmed/34088893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00511-2
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