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Lipotoxicity suppresses the synthesis of growth hormone in pituitary somatotrophs via endoplasmic reticulum stress

Lipotoxicity has been shown to cause dysfunction of many organs and tissues. However, it is unclear whether lipotoxicity is harmful to the somatotrophs, a kind of cell that synthesize growth hormone (GH) in the pituitary. In this study, we performed an epidemiological study, serum levels of triglyce...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Gong, Ying, Yang, Jianmei, Wei, Shuoshuo, Yang, Rui, Gao, Ling, Shao, Shanshan, Zhao, Jiajun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178284/
https://ncbi.nlm.nih.gov/pubmed/33943005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16532
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