A Phase I Trial Evaluating the Effects of Plerixafor, G-CSF, and Azacitidine for the Treatment of Myelodysplastic Syndromes

Interactions between the bone marrow microenvironment and MDS tumor clones play a role in pathogenesis and response to treatment. We hypothesized G-CSF and plerixafor may enhance sensitivity to azacitidine in MDS. 28 patients with MDS were treated with plerixafor, G-CSF and azacitidine with a standa...

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Publicat a:Leuk Lymphoma
Autors principals: Huselton, Eric, Rettig, Michael P., Fletcher, Theresa, Ritchey, Julie, Gehrs, Leah, McFarland, Kyle, Christ, Stephanie, Eades, William C., Trinkaus, Kathryn, Romee, Rizwan, Kulkarni, Shashikant, Ghobadi, Armin, Abboud, Camille, Cashen, Amanda F., Stockerl-Goldstein, Keith, Uy, Geoffrey L., Vij, Ravi, Westervelt, Peter, DiPersio, John F., Schroeder, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178174/
https://ncbi.nlm.nih.gov/pubmed/33467957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2021.1872068
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