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Reprogrammable Gel Electrophoresis Detection Assay Using CRISPR-Cas12a and Hybridization Chain Reaction

Hybridization chain reaction (HCR) is a DNA-based target-induced cascade reaction. Due to its unique enzyme-free amplification feature, HCR is often employed for sensing applications. Much like DNA nanostructures that have been designed to respond to a specific stimulus, HCR employs nucleic acids th...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Kachwala, Mahera J., Smith, Christopher W., Nandu, Nidhi, Yigit, Mehmet V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177748/
https://ncbi.nlm.nih.gov/pubmed/33404234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c04949
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