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On the effect of phylogenetic correlations in coevolution-based contact prediction in proteins

Coevolution-based contact prediction, either directly by coevolutionary couplings resulting from global statistical sequence models or using structural supervision and deep learning, has found widespread application in protein-structure prediction from sequence. However, one of the basic assumptions...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Rodriguez Horta, Edwin, Weigt, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177639/
https://ncbi.nlm.nih.gov/pubmed/34029316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008957
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