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Site-Specific Chemical Fatty-acylation for Gain-of-Function Analysis of Protein S-Palmitoylation in Live Cells
Protein S-palmitoylation, or S-fatty-acylation, regulates many fundamental cellular processes in eukaryotes. Herein, we present a chemical fatty-acylation approach that involves site-specific incorporation of cycloalkyne-containing unnatural amino acids and subsequent bioorthogonal reactions with fa...
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| Udgivet i: | Chem Commun (Camb) |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8177487/ https://ncbi.nlm.nih.gov/pubmed/33094750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cc06073a |
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