Can Some Anticancer Treatments Preserve the Ovarian Reserve?

BACKGROUND: Preventing premature ovarian failure (POF) is a major challenge in oncology. With conventional regimens, cytotoxicity‐associated POF involves primordial follicles (PF) pool depletion by apoptosis or overactivation mechanisms, notably mediated by the ABL/TAp63 and PI3K/Akt/mTOR pathways....

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Vydáno v:Oncologist
Hlavní autoři: Vallet, Nicolas, Boissel, Nicolas, Elefant, Elisabeth, Chevillon, Florian, Pasquer, Hélène, Calvo, Charlotte, Dhedin, Nathalie, Poirot, Catherine
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2021
Témata:
Gynecologic Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176995/
https://ncbi.nlm.nih.gov/pubmed/33458904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/onco.13675
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