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Alternative splicing in aging and longevity

Alternative pre-mRNA splicing increases the complexity of the proteome that can be generated from the available genomic coding sequences. Dysregulation of the splicing process has been implicated in a vast repertoire of diseases. However, splicing has recently been linked to both the aging process i...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genet
Hauptverfasser: Bhadra, Malini, Howell, Porsha, Dutta, Sneha, Heintz, Caroline, Mair, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176884/
https://ncbi.nlm.nih.gov/pubmed/31834493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-02094-6
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