Pharmacokinetics and Biodistribution of [(89)Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients

Six-transmembrane epithelial antigen of prostate-1 (STEAP1) is a newly identified target in prostate cancer. The use of radiolabeled STEAP1-targeting antibodies with positron emission tomography (PET) may allow for detection of sites of metastatic prostate cancer and may refine patient selection for...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: O'Donoghue, Joseph A., Danila, Daniel C., Pandit-Taskar, Neeta, Beylergil, Volkan, Cheal, Sarah M., Fleming, Stephen E., Fox, Josef J., Ruan, Shutian, Zanzonico, Pat B., Ragupathi, Govind, Lyashchenko, Serge K., Williams, Simon P., Scher, Howard I., Fine, Bernard M., Humm, John L., Larson, Steven M., Morris, Michael J., Carrasquillo, Jorge A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176438/
https://ncbi.nlm.nih.gov/pubmed/31117485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00326
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