Pharmacokinetics and Biodistribution of [(89)Zr]Zr-DFO-MSTP2109A Anti-STEAP1 Antibody in Metastatic Castration-Resistant Prostate Cancer Patients

Six-transmembrane epithelial antigen of prostate-1 (STEAP1) is a newly identified target in prostate cancer. The use of radiolabeled STEAP1-targeting antibodies with positron emission tomography (PET) may allow for detection of sites of metastatic prostate cancer and may refine patient selection for...

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Veröffentlicht in:Mol Pharm
Hauptverfasser: O'Donoghue, Joseph A., Danila, Daniel C., Pandit-Taskar, Neeta, Beylergil, Volkan, Cheal, Sarah M., Fleming, Stephen E., Fox, Josef J., Ruan, Shutian, Zanzonico, Pat B., Ragupathi, Govind, Lyashchenko, Serge K., Williams, Simon P., Scher, Howard I., Fine, Bernard M., Humm, John L., Larson, Steven M., Morris, Michael J., Carrasquillo, Jorge A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176438/
https://ncbi.nlm.nih.gov/pubmed/31117485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00326
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