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β3-integrin Leu33Pro gain of function variant does not modulate inflammatory activity in human derived macrophages in diabetes

Objective: We aimed to investigate the association between the Leu33Pro (rs5918) polymorphism in β3-integrin with diabetic complications and inflammatory function of macrophages depending on the genotype in subjects with diabetes mellitus. Material and methods: We determined the Leu33Pro polymorphis...

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Vydáno v:Int J Med Sci
Hlavní autoři: Helmer, Philipp, Damm, Ellen, Schiekofer, Stephan, Roomp, Kirsten, Schneider, Jochen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176178/
https://ncbi.nlm.nih.gov/pubmed/34104098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.55648
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