Acalabrutinib plus Obinutuzumab in Treatment-Naïve and Relapsed/Refractory Chronic Lymphocytic Leukemia

Acalabrutinib is a selective irreversible Bruton tyrosine kinase (BTK) inhibitor that does not affect IL2-associated tyrosine kinase or antibody-dependent cellular cytotoxicity, making it an attractive candidate for combination therapy with anti-CD20 antibodies. We investigated acalabrutinib plus ob...

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Bibliografski detalji
Izdano u:Cancer Discov
Glavni autori: Woyach, Jennifer A., Blachly, James S., Rogers, Kerry A., Bhat, Seema A., Jianfar, Mojgan, Lozanski, Gerard, Weiss, David M., Andersen, Barbara L., Gulrajani, Michael, Frigault, Melanie M., Hamdy, Ahmed, Izumi, Raquel, Munugalavadla, Veerendra, Quah, Cheng, Wang, Min-Hui, Byrd, John C.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176161/
https://ncbi.nlm.nih.gov/pubmed/31915195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-1130
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