The Canonical Wnt Signaling Pathway Inhibits the Glucocorticoid Receptor Signaling Pathway in the Trabecular Meshwork

Glucocorticoid-induced glaucoma is a secondary open-angle glaucoma. About 40% of the general population may develop elevated intraocular pressure on prolonged glucocorticoid treatment secondary to damages in the trabecular meshwork (TM), a tissue that regulates intraocular pressure. Therefore, ident...

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Vydáno v:Am J Pathol
Hlavní autoři: Sugali, Chenna Kesavulu, Rayana, Naga Pradeep, Dai, Jiannong, Peng, Michael, Harris, Sherri L., Webber, Hannah C., Liu, Shaohui, Dixon, Stephan G., Parekh, Priyanka H., Martin, Elizabeth A., Cantor, Louis B., Fellman, Ronald L., Godfrey, David G., Butler, Michelle R., Emanuel, Matthew E., Grover, Davinder S., Smith, Oluwatosin U., Clark, Abbot F., Raghunathan, Vijay Krishna, Mao, Weiming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2021
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176142/
https://ncbi.nlm.nih.gov/pubmed/33705750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2021.02.018
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