Existence of the Canonical Wnt Signaling Pathway in the Human Trabecular Meshwork

PURPOSE. We previously discovered elevated levels of secreted frizzled-related protein 1 (sFRP1), the Wnt signaling pathway inhibitor, in the glaucomatous trabecular meshwork (GTM), and found that key canonical Wnt signaling pathway genes are expressed in the trabecular meshwork (TM). The purpose of...

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Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Mao, Weiming, Millar, J. Cameron, Wang, Wan-Heng, Silverman, Sean M., Liu, Yang, Wordinger, Robert J., Rubin, Jeffrey S., Pang, Iok-Hou, Clark, Abbot F.
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607241/
https://ncbi.nlm.nih.gov/pubmed/22956608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9664
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