Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Antimicrobial resistance in Neisseria gonorrhoeae is threatening the treatment and control of gonorrhea globally, and new treatment options are imperative. Utilizing our dynamic in vitro hollow fiber infection model (HFIM), we examined the pharmacodynamics of the first-in-class spiropyrimidinetrione...

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Sparad:
Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Jacobsson, Susanne, Golparian, Daniel, Oxelbark, Joakim, Alirol, Emilie, Franceschi, Francois, Gustafsson, Tomas N., Brown, David, Louie, Arnold, Drusano, George, Unemo, Magnus
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175963/
https://ncbi.nlm.nih.gov/pubmed/34093206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.682135
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