A functional motif of long noncoding RNA Nron against osteoporosis

Long noncoding RNAs are widely implicated in diverse disease processes. Nonetheless, their regulatory roles in bone resorption are undefined. Here, we identify lncRNA Nron as a critical suppressor of bone resorption. We demonstrate that osteoclastic Nron knockout mice exhibit an osteopenia phenotype...

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Publicat a:Nat Commun
Autors principals: Jin, Fujun, Li, Junhui, Zhang, Yong-Biao, Liu, Xiangning, Cai, Mingxiang, Liu, Meijing, Li, Mengyao, Ma, Cui, Yue, Rui, Zhu, Yexuan, Lai, Renfa, Wang, Zuolin, Ji, Xunming, Wei, Huawei, Dong, Jun, Liu, Zhiduo, Wang, Yifei, Sun, Yao, Wang, Xiaogang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175706/
https://ncbi.nlm.nih.gov/pubmed/34083547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23642-7
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