Compartmentalized Reconstitution of Post-squalene Pathway for 7-Dehydrocholesterol Overproduction in Saccharomyces cerevisiae

7-Dehydrocholesterol (7-DHC) is the direct precursor to manufacture vitamin D(3). Our previous study has achieved 7-DHC synthesis in Saccharomyces cerevisiae based on the endogenous post-squalene pathway. However, the distribution of post-squalene enzymes between the endoplasmic reticulum (ER) and l...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Guo, Xiao-Jing, Yao, Ming-Dong, Xiao, Wen-Hai, Wang, Ying, Zhao, Guang-Rong, Yuan, Ying-Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175624/
https://ncbi.nlm.nih.gov/pubmed/34093477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.663973
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