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Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II
Complex formation between hexokinase-II (HKII) and the mitochondrial VDAC1 is crucial to cell growth and survival. We hypothesize that HKII first inserts into the outer membrane of mitochondria (OMM) and then interacts with VDAC1 on the cytosolic leaflet of OMM to form a binary complex. To systemati...
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| Pubblicato in: | Commun Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8175357/ https://ncbi.nlm.nih.gov/pubmed/34083717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02205-y |
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