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Dissecting nucleotide selectivity in viral RNA polymerases

Designing antiviral therapeutics is of great concern per current pandemics caused by novel coronavirus or SARS-CoV-2. The core polymerase enzyme in the viral replication/transcription machinery is generally conserved and serves well for drug target. In this work we briefly review structural biology...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Long, Chunhong, Romero, Moises Ernesto, La Rocco, Daniel, Yu, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175102/
https://ncbi.nlm.nih.gov/pubmed/34104356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.06.005
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