Ibrutinib Treatment for First-Line and Relapsed/Refractory Chronic Lymphocytic Leukemia: Final Analysis of the Pivotal Phase Ib/II PCYC-1102 Study

PURPOSE: The safety and efficacy of ibrutinib, a once-daily Bruton’s tyrosine kinase (BTK) inhibitor, in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) was demonstrated in this phase Ib/II study. Extended follow-up up to 8 years is described, representing the longest follow-up for...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Byrd, John C., Furman, Richard R., Coutre, Steven E., Flinn, Ian W., Burger, Jan A., Blum, Kristie, Sharman, Jeff P., Wierda, William, Zhao, Weiqiang, Heerema, Nyla A., Luan, Ying, Liu, Emily A., Dean, James P., O’Brien, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8175012/
https://ncbi.nlm.nih.gov/pubmed/32209572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-2856
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