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Cardiac‐Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice

BACKGROUND: Orai3 is a mammalian‐specific member of the Orai family (Orai1‒3) and a component of the store‐operated Ca(2+) entry channels. There is little understanding of the role of Orai channels in cardiomyocytes, and its role in cardiac function remains unexplored. Thus, we developed mice lackin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Heart Assoc
मुख्य लेखकों: Gammons, Jesse, Trebak, Mohamed, Mancarella, Salvatore
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174158/
https://ncbi.nlm.nih.gov/pubmed/33849280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.019486
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