Polyamine Modulation of Anticonvulsant Drug Response: A Potential Mechanism Contributing to Pharmacoresistance in Chronic Epilepsy

Despite the development of numerous novel anticonvulsant drugs, ∼30% of epilepsy patients remain refractory to antiepileptic drugs (AEDs). Many established and novel AEDs reduce hyperexcitability via voltage- and use-dependent inhibition of voltage-gated Na(+) channels. For the widely used anticonvu...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Beckonert, Niklas Michael, Opitz, Thoralf, Pitsch, Julika, Soares da Silva, Patrício, Beck, Heinz
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174136/
https://ncbi.nlm.nih.gov/pubmed/29789377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0640-18.2018
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars