Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever

Prostaglandin E(2) (PGE(2)) in the hypothalamus is a principal mediator of the febrile response. However, the role of organic anion transporting polypeptide 2A1 (OATP2A1/SLCO2A1), a prostaglandin transporter, in facilitating this response is unknown. Here, we investigated the effect of Slco2a1 defic...

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Pubblicato in:J Neurosci
Autori principali: Nakamura, Yoshinobu, Nakanishi, Takeo, Shimada, Hiroaki, Shimizu, Junya, Aotani, Rika, Maruyama, Shio, Higuchi, Kei, Okura, Takashi, Deguchi, Yoshiharu, Tamai, Ikumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2018
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174131/
https://ncbi.nlm.nih.gov/pubmed/29899035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3276-17.2018
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