Prostaglandin Transporter (PGT/SLCO2A1) Protects the Lung from Bleomycin-Induced Fibrosis

Prostaglandin (PG) E(2) exhibits an anti-fibrotic effect in the lung in response to inflammatory reactions and is a high-affinity substrate of PG transporter (SLCO2A1). The present study aimed to evaluate the pathophysiological relevance of SLCO2A1 to bleomycin (BLM)-induced pulmonary fibrosis in mi...

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Pubblicato in:PLoS One
Autori principali: Nakanishi, Takeo, Hasegawa, Yoshitaka, Mimura, Reo, Wakayama, Tomohiko, Uetoko, Yuka, Komori, Hisakazu, Akanuma, Shin-ichi, Hosoya, Ken-ichi, Tamai, Ikumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414486/
https://ncbi.nlm.nih.gov/pubmed/25923111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123895
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