Characterization of Plasma Cell-Free DNA Integrity Using Droplet-Based Digital PCR: Toward the Development of Circulating Tumor DNA-Dedicated Assays

Background: Cellular-cell free-DNA (ccfDNA) is being explored as a diagnostic and prognostic tool for various diseases including cancer. Beyond the evaluation of the ccfDNA mutational status, its fragmentation has been investigated as a potential cancer biomarker in several studies. However, probabl...

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Publicado en:Front Oncol
Autores principales: Poulet, Geoffroy, Garlan, Fanny, Garrigou, Sonia, Zonta, Eleonora, Benhaim, Leonor, Carrillon, Marie-Jennifer, Didelot, Audrey, Le Corre, Delphine, Mulot, Claire, Nizard, Philippe, Ginot, Frederic, Boutonnet-Rodat, Audrey, Blons, Helene, Bachet, Jean-Baptiste, Taïeb, Julien, Zaanan, Aziz, Geromel, Vanna, Pellegrina, Laurence, Laurent-Puig, Pierre, Wang-Renault, Shu-Fang, Taly, Valerie
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174096/
https://ncbi.nlm.nih.gov/pubmed/34094923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.639675
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